Avanafil vs Viagra

Improper penile erection is a much more complex phenomenon, involving interactions between biological, neural, psychological, vascular, and hormonal elements. Erectile dysfunction is one of the most prevalent sexual problems, whether among the younger or the older adults. Some of the major physical causes for such issues are stressful lifestyle, inadequate sleep, alcohol or tobacco consumption, or even substance abuse. Thanks to some highly effective medications like Avanafil, Viagra, and so on, one may get rid of such problems forever. 

What is Avanafil? 

As a phosphodiesterase type 5 inhibitor, Avanafil  is a commonly prescribed medication against erectile dysfunction in males. Appearing in the form of white crystalline powder, Avanafil is found to have significant selectivity of phosphodiesterase type 5 and a higher selectivity against phosphodiesterase type 1 and phosphodiesterase type 6.  

This popular medication got its official approval from the United State Food and Drug Administration (USFDA) for the treatment of erectile dysfunction on April 27, 2012; also by EMA on June 21, 2013. (source)

What is Viagra?

Viagra is a popular branded medication name, having the salt of sildenafil citrate; used for treating erectile dysfunction in men, that is invented and marketed by Pfizer. 

Key Differences between Avanafil vs Viagra Explained 

Parameters	Avanafil	Viagra
Erection Duration	6 to 7 hours	4 hours
Mechanism of Action	Works by inhibiting the effect of PDE5. This inhibition leads to penile erection due to the inflow of blood into the area.	Being a PDE5 inhibitor, it widens the blood vessels in order to allow more flow of blood, eventually bringing relaxaion to the blood vessels. Blood flow is pushed towards the penile area, eventually achieving and maintaining a proper erection.
Dosage strengths available	50 mg /100 mg /200 mg	25 mg, 50 mg, 100 mg, 150mg, 200mg
Timing of Consumption	30 minutes prior to the sexual act	30–60 minutes prior to the sexual act
Dissolution duration	45 minutes	20 to 30 minutes (however, having a high fat content meal might affect this duration)
Side effects	The most commonly documented adverse reactions include back pain, nasal congestion, headache, flushing, and nasopharyngitis.	Prolonged and painful erections, flushing or reddening, dizziness, heart problems, gastrointestinal problems, seizures or convulsions, blurred vision or changes in colour vision, muscle pains.
Storage temp.	20°C – 25°C	20–25°C

Which one is better : Avanafil or Viagra? 

Both the medications have got their respective pros and cons. But so far having a longer duration of penile erection is concerned, avanafil holds an upper hand with a 6 to 7 hours capacity; while that of viagra is about 4 hours. 

Yet, having said that, it is purely a matter of individual requirement, preference, and most importantly suitability of one’s body (involving the kind of adverse effects these are capable to inflict on different individuals); that are required to be considered before consuming either of these two medications. 

Hence it is advised to only go for a thorough medical consultation from an authorized medical practitioner, before finalizing on any of these two drugs.

Other Drug Interactions – Avanafil vs Viagra  

Both of these medications are phosphodiesterase type 5 (PDE5) inhibitors, and have similar interactions with other drugs. Hence the following drugs should be avoided while receiving a treatment involving either of these two drugs:

• Various forms of nitrates, such as isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat)
• Certain blood pressure drugs, such as calcium channel blockers or even alpha-blockers, that is used in cses of enlarged prostates
• Certain pulmonary hypertension drugs like riociguat (Adempas)
• Protease inhibitors, a class of HIV medications
• Antifungal drugs, such as ketoconazole and itraconazole (Onmel, Sporanox)
• Antibacterial drugs, such as clarithromycin (Biaxin)

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