Buy Avanafil Tablets Online for Erectile Dysfunction Problems
Even in these modern times and after so many scientific and medical revolutions, sexual problems remain taboo for many. Out of 30 million men (approximately) per year, only about 20 lakh men turn up to voice their problems and get the required help; the rest just shy away from these issues into silent suffering and depression.
Such patients need to understand that there are suitable and effective drugs available in the market to help them out of this. Avanafil happens to be quite a magical pill when it comes to treating sexual problems like erectile dysfunction or ED among men. Let us understand the basics of this medication for penile erection issues herein.
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What is Avanafil?
Being a phosphodiesterase type 5 inhibitor, Avanafil is a much-recommended medication for the treatment of erectile dysfunction in males. White crystalline powder in appearance, Avanafil is found to have significant selectivity of phosphodiesterase type 5 and a higher selectivity against phosphodiesterase type 1 and phosphodiesterase type 6.
This popular medication got its official approval from the United State Food and Drug Administration (USFDA) for the treatment of erectile dysfunction on April 27, 2012, and also by EMA on June 21, 2013. (source)
What is Avanafil used for?
Avanafil is used to treat erectile dysfunction (ED). As a phosphodiesterase type 5 inhibitor, avanafil has been proven to have successfully projecting a penial erection of six to seven hours.
How does Avanafil work?
As a phosphodiesterase (PDE) type 5 inhibitor, avanafil is responsible for blocking the phosphodiesterase enzyme and preventing the degradation of cGMP. The increased levels of cGMP induce vasodilation, thereby stimulating an increased blood flow in the penial area. Avanafil’s mechanism of action sets off once the nitric oxide is released, along with some sort of sexual stimulation.
What is the Recommended Dosage for Avanafil?
The recommended initial dose of avanafil is 100 mg, to be administered orally approximately 20 to 30 minutes before to sexual performance.
Based upon effectiveness and tolerability, the dose can be increased higher up to 200 mg maximum dose or decreased lower up to 50 mg.
This medication can be taken with or without regard to food.
It should certainly, not be used by patients with severe renal or hepatic impairment.
How long does Avanafil take to come into effect?
This medication needs to be consumed some 15 minutes before the sexual act to have a desirable penial erection.
Avanafil is quite an advantageous medication as it has a very fast onset of action, as compared to that of the other PDE5 inhibitors. It is absorbed quickly, reaching a maximum serum concentration in about thirty to forty-five minutes.
How long will its results last?
Avanafil is quite a popular choice for getting a penial erection. It is capable of producing a penial erection of 6 to 7 hours duration.
Common Long term and Short term Side effects of Avanafil
After the clinical trials, the most commonly documented adverse reactions include back pain, nasal congestion, headache, flushing, and nasopharyngitis. These side effects were seen in 2% or more of the patients studied in clinical trials.
The other adverse reactions that occurred in less than 2% of the patients included upper respiratory infection (URI), bronchitis, sinusitis, sinus congestion, influenza, hypertension, nausea, dyspepsia, constipation, back pain, dizziness, arthralgia, and diarrhea.
Other Drug Interactions – What to avoid when taking Avanafil?
The effect of avanafil in combination with any organic nitrate is contraindicated. In a life-threatening situation, nitrate medication can only be administered at least 12 hours after the last dose of avanafil was administered.
Caution must be taken when using avanafil concomitantly with alpha-blocker medications and antihypertensive medications.
The use of alcohol along with avanafil is not recommended due to the increased potentiation of Blood Pressure lowering effects leading to orthostatic hypotension, headache, and dizziness.
When to consult a doctor?
One should always consult an authorized doctor or medical practitioner before consuming this medication, as it may react differently for different people. Also, it might inflict different side effects on some; hence they should go for an immediate consultation to deal with the issues in the most appropriate way.