Everything about the Different Uses of Tadalafil
There are certain medical conditions that come with the additional burden of social stigma and taboos. Patients get worried about being judged and left out, and hence they shy away from getting the right diagnosis and appropriate treatment. Sexual problems are such problems. Fortunately, there are medications like Tadalafil, that are quite impressive in addressing sexual issues along with some other medical conditions. Â
What is Tadalafil? Â
Tadalafil is quite a well-known phosphodiesterase type 5 inhibitor (PDE5 inhibitor) i,e vasodilatation pharmaceutical drug. It is primarily used in addressing the symptoms of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy. It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH.Â
What is Tadalafil used for?Â
The chemical compound of Tadalafil becomes the base salt for numerous medications, which are used in multiple treatments. However, Tadalafil is more commonly used for erectile dysfunction. However, there are a few other medical conditions where Tadalafil is used; as mentioned below:Â Â
1. Erectile DysfunctionÂ
Erectile Dysfunction is a condition when there is a lack of blood flow in the penis. This makes a man unable to attain and maintain the erection required during sexual intercourse.Â
This type of medical issue might arise out of multiple reasons like physical complications post an injury or ailments or even due to some psychological conditions such as anxiety, stress, depression, etc. It might also occur out of chronic lifestyle factors such as obesity, smoking, drinking, etc.
2. Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a condition when there is a non-cancerous growth of the prostate gland, which is a walnut-sized gland located just below the bladder that secretes fluid to transport the sperm.Â
As the prostate surrounds the urethra, the tube that carries urine out of our body, an increase in the size of this gland may lead to difficulties in urination, weak urinary stream, frequent urination, loss of bladder control, etc.Â
3. Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension (PAH) is a condition when there is increased blood pressure within the arteries of the lungs; which gives rise to breathlessness, fainting, tiredness, chest pain, swelling of legs, and increased heartbeat.Â
4. Premature ejaculationÂ
In such a condition, a man fails to maintain the erection required in sexual intercourse, and the reasons responsible for its occurrence might be similar to that of erectile dysfunction.Â
How to take Tadalafil for best use?
Usually, the initial dose for Tadalafil tablets for addressing the early symptoms of ED is 10 mg. However, those who are facing much problem with erection might require a 40 mg tablet once a day or two 20 mg tablets a day.Â
Having said that, the daily dosage for any patient should be strictly as per a doctor’s recommendation. Based upon the effectiveness and tolerability of individual patients, the dose can be increased or decreased as per a doctor’s guidance.Â
It can be taken about 30 minutes before the sexual act.Â
The tablet needs to be swallowed as a whole, with a glass of water. It should not be broken or crushed or chewed.Â
How does Tadalafil work?
Our body produces nitric oxide at nerve terminals and endothelial cells, which stimulates the synthesis of cyclic guanosine monophosphate; which is again commonly known as cyclic GMP or cGMP, in the smooth muscle cells of the corpus cavernosum penis. The cGMP relaxes smooth muscle and increases blood flow to the corpus cavernosum.Â
In the simplest terms, PDE5 inhibitors like Tadalafil, work by increasing blood flow toward the penis. They block the specific enzyme in the blood vessels. It relaxes the blood vessels, resulting in a much-increased blood flow toward the penis, in order to produce a desirable erection for proper intercourse and get optimum sexual pleasure as well.Â